TY - UNPB
T1 - Maternal depression and child human capital: A genetic instrumental-variable approach
AU - Menta, Giorgia
AU - Lepinteur, Anthony
AU - Clark, Andrew
AU - Ghislandi, Simone
AU - D'Ambrosio, Conchita
N1 - MedRxiv is a free online archive and distribution server for complete but unpublished manuscripts (preprints) in the medical, clinical, and related health sciences.
PY - 2021/2/12
Y1 - 2021/2/12
N2 - We here address the causal relationship between maternal depression and child human capital using UK cohort data. We exploit the conditionally-exogenous variation in mothers’ genomes in an instrumental-variable approach, and describe the conditions under which mother’s genetic variants can be used as valid instruments. An additional episode of maternal depression between the child’s birth up to age nine reduces both their cognitive and non-cognitive skills by 20 to 45% of a SD throughout adolescence. Our results are robust to a battery of sensitivity tests addressing, among others, concerns about pleiotropy and the maternal transmission of genes to her child.
AB - We here address the causal relationship between maternal depression and child human capital using UK cohort data. We exploit the conditionally-exogenous variation in mothers’ genomes in an instrumental-variable approach, and describe the conditions under which mother’s genetic variants can be used as valid instruments. An additional episode of maternal depression between the child’s birth up to age nine reduces both their cognitive and non-cognitive skills by 20 to 45% of a SD throughout adolescence. Our results are robust to a battery of sensitivity tests addressing, among others, concerns about pleiotropy and the maternal transmission of genes to her child.
KW - Mendelian Randomisation
KW - Maternal Depression
KW - Human Capital
KW - Instrumental Variables
KW - ALSPAC
UR - http://dx.doi.org/10.1101/2021.02.11.21251547
U2 - 10.1101/2021.02.11.21251547
DO - 10.1101/2021.02.11.21251547
M3 - Working paper
BT - Maternal depression and child human capital: A genetic instrumental-variable approach
PB - MedRxiv
ER -