TY - JOUR
T1 - Pace of aging, family environment and cognitive skills in children and adolescents
AU - Niccodemi, Gianmaria
AU - Menta, Giorgia
AU - Turner, Jonathan
AU - D’Ambrosio, Conchita
PY - 2022/12
Y1 - 2022/12
N2 - Pace of aging is an epigenetic clock which captures the speed at which someone is biologically aging compared to the chronological-age peers. We here use data from the Avon Longitudinal Study of Parents and Children (ALSPAC) to investigate the interrelation between the study children's parental social class at birth, and their pace of aging and cognitive skills measures in childhood and adolescence. We show that children from lower parental social classes display faster pace of aging and that the social class gradient in pace of aging is strongest in adolescence. About one third of this association can be explained by other socio-economic and demographic covariates, as well as life events. Similarly, study children's pace of aging manifests a negative association with their measures of cognitive skills in late adolescence only. This association becomes stronger as the contemporary pace of aging of the mother becomes faster. Our results seem to identify adolescence as the period of life when pace of aging, family environment and cognitive skills measures begin to interact.
AB - Pace of aging is an epigenetic clock which captures the speed at which someone is biologically aging compared to the chronological-age peers. We here use data from the Avon Longitudinal Study of Parents and Children (ALSPAC) to investigate the interrelation between the study children's parental social class at birth, and their pace of aging and cognitive skills measures in childhood and adolescence. We show that children from lower parental social classes display faster pace of aging and that the social class gradient in pace of aging is strongest in adolescence. About one third of this association can be explained by other socio-economic and demographic covariates, as well as life events. Similarly, study children's pace of aging manifests a negative association with their measures of cognitive skills in late adolescence only. This association becomes stronger as the contemporary pace of aging of the mother becomes faster. Our results seem to identify adolescence as the period of life when pace of aging, family environment and cognitive skills measures begin to interact.
KW - Age acceleration
KW - Epigenetic age
KW - DNA methylation
KW - Pace of aging
KW - ALSPAC
KW - Social class
KW - Social environment
UR - http://www.scopus.com/inward/record.url?scp=85141510084&partnerID=8YFLogxK
UR - https://www.mendeley.com/catalogue/8eb1db34-5cda-3c14-b165-09235c1c1708/
U2 - 10.1016/j.ssmph.2022.101280
DO - 10.1016/j.ssmph.2022.101280
M3 - Article
C2 - 36387015
SN - 2352-8273
VL - 20
JO - SSM - Population Health
JF - SSM - Population Health
M1 - 101280
ER -