TY - JOUR
T1 - Timed up-and-go performance is associated with objectively measured life space in patients 3 months after ischemic stroke
T2 - a cross-sectional observational study
AU - Rössler, Roland
AU - Rommers, Nikki
AU - Kim, Eun-Kyeong
AU - Lendra, Laura
AU - Sofios, Alexander
AU - Giannouli, Eleftheria
AU - Portegijs, Erja
AU - Rantanen, Taina
AU - Infanger, Denis
AU - Bridenbaugh, Stephanie
AU - Engelter, Stefan T.
AU - Schmidt-Trucksäss, Arno
AU - Weibel, Robert
AU - Peters, Nils
AU - Hinrichs, Timo
N1 - Open access funding provided by University of Basel. We would like to thank the Swiss National Science Foundation who funded the project MOBITEC-Stroke (“Recovery of mobility function and life-space mobility after ischemic stroke”, Project No. 32003B_182681).
PY - 2022
Y1 - 2022
N2 - Background: Stroke is a common cause of mobility limitation, including a reduction in life space. Life space is defined as the spatial extent in which a person moves within a specified period of time. We aimed to analyze patients’ objective and self-reported life space and clinical stroke characteristics. Methods: MOBITEC-Stroke is a prospective observational cohort study addressing poststroke mobility. This cross-sectional analysis refers to 3-month data. Life space was assessed by a portable tracking device (7 consecutive days) and by self-report (Life-Space Assessment; LSA). We analysed the timed up-and-go (TUG) test, stroke severity (National Institutes of Health Stroke Scale; NIHSS), and the level of functional outcome (modified Rankin Scale; mRS) in relation to participants’ objective (distance- and area-related life-space parameters) and self-reported (LSA) life space by multivariable linear regression analyses, adjusted for age, sex, and residential area. Results: We included 41 patients, mean age 70.7 (SD11.0) years, 29.3% female, NIHSS score 1.76 (SD1.68). We found a positive relationship between TUG performance and maximum distance from home (p = 0.006), convex hull area (i.e. area enclosing all Global Navigation Satellite System [GNSS] fixes, represented as a polygon linking the outermost points; p = 0.009), perimeter of the convex hull area (i.e. total length of the boundary of the convex hull area; p = 0.008), as well as the standard ellipse area (i.e. the two-dimensional ellipse containing approximately 63% of GNSS points; p = 0.023), in multivariable regression analyses. Conclusion: The TUG, an easily applicable bedside test, seems to be a useful indicator for patients’ life space 3 months poststroke and may be a clinically useful measure to document the motor rehabilitative process.
AB - Background: Stroke is a common cause of mobility limitation, including a reduction in life space. Life space is defined as the spatial extent in which a person moves within a specified period of time. We aimed to analyze patients’ objective and self-reported life space and clinical stroke characteristics. Methods: MOBITEC-Stroke is a prospective observational cohort study addressing poststroke mobility. This cross-sectional analysis refers to 3-month data. Life space was assessed by a portable tracking device (7 consecutive days) and by self-report (Life-Space Assessment; LSA). We analysed the timed up-and-go (TUG) test, stroke severity (National Institutes of Health Stroke Scale; NIHSS), and the level of functional outcome (modified Rankin Scale; mRS) in relation to participants’ objective (distance- and area-related life-space parameters) and self-reported (LSA) life space by multivariable linear regression analyses, adjusted for age, sex, and residential area. Results: We included 41 patients, mean age 70.7 (SD11.0) years, 29.3% female, NIHSS score 1.76 (SD1.68). We found a positive relationship between TUG performance and maximum distance from home (p = 0.006), convex hull area (i.e. area enclosing all Global Navigation Satellite System [GNSS] fixes, represented as a polygon linking the outermost points; p = 0.009), perimeter of the convex hull area (i.e. total length of the boundary of the convex hull area; p = 0.008), as well as the standard ellipse area (i.e. the two-dimensional ellipse containing approximately 63% of GNSS points; p = 0.023), in multivariable regression analyses. Conclusion: The TUG, an easily applicable bedside test, seems to be a useful indicator for patients’ life space 3 months poststroke and may be a clinically useful measure to document the motor rehabilitative process.
KW - GPS
KW - Mobility capacity
KW - Mobility limitation
KW - Quality of life
KW - Spatial behaviour
UR - http://www.scopus.com/inward/record.url?scp=85144719916&partnerID=8YFLogxK
UR - https://www.mendeley.com/catalogue/17d5a94e-154e-3d69-bc97-b102c74a915e/
U2 - 10.1007/s00415-022-11524-x
DO - 10.1007/s00415-022-11524-x
M3 - Article
C2 - 36547716
AN - SCOPUS:85144719916
SN - 0340-5354
VL - 270
SP - 1999
EP - 2009
JO - Journal of Neurology
JF - Journal of Neurology
IS - 4
ER -